Chemical Name,Chemical ID,CAS RN,Gene Symbol,Gene ID,Interaction,Interaction Actions,Reference Count,Organism Count
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine,D019307,84477-87-2,GDF15,9518,[SB 203580 co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] inhibits the reaction [jasplakinolide results in increased expression of GDF15 protein],affects^cotreatment|decreases^reaction|increases^expression,1,1
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine,D019307,84477-87-2,GDF15,9518,[SB 203580 co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] inhibits the reaction [latrunculin B results in increased expression of GDF15 protein],affects^cotreatment|decreases^reaction|increases^expression,1,1
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine,D019307,84477-87-2,GDF15,9518,[SB 203580 co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GDF15 protein],affects^cotreatment|decreases^reaction|increases^expression,1,1
1-Butanol,D020001,71-36-3,GDF15,9518,[[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of GDF15 mRNA,affects^cotreatment|increases^abundance|increases^expression,1,1
1-Methyl-3-isobutylxanthine,D015056,28822-58-4,GDF15,9518,[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of GDF15 mRNA,affects^cotreatment|increases^expression,1,1
1-Methyl-3-isobutylxanthine,D015056,28822-58-4,GDF15,9518,[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of GDF15 mRNA,affects^cotreatment|decreases^expression,1,1
1-Methyl-4-phenylpyridinium,D015655,48134-75-4,AMH,268,1-Methyl-4-phenylpyridinium results in decreased expression of AMH mRNA,decreases^expression,1,1
1-Methyl-4-phenylpyridinium,D015655,48134-75-4,GDF15,9518,1-Methyl-4-phenylpyridinium results in increased expression of GDF15 mRNA,increases^expression,1,1
"2,2',4,4',5-brominated diphenyl ether",C477694,,GDF15,9518,"2,2',4,4',5-brominated diphenyl ether results in increased expression of GDF15 mRNA",increases^expression,1,1
"2,2',4,4'-tetrabromodiphenyl ether",C511295,,GDF15,9518,"2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of GDF15 protein",decreases^expression,1,1
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one,C093973,,GDF15,9518,2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [rottlerin results in increased expression of GDF15 protein],decreases^reaction|increases^expression,1,1
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one,C093973,,GDF15,9518,2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Troglitazone results in increased expression of GDF15 protein],decreases^reaction|increases^expression,1,1
"2,3-bis(3'-hydroxybenzyl)butyrolactone",C029497,76543-15-2,GDF15,9518,"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of GDF15 mRNA",affects^cotreatment|decreases^expression,1,1
"2,5,2',5'-tetrachlorobiphenyl",C009407,35693-99-3,GDF15,9518,"2,5,2',5'-tetrachlorobiphenyl results in increased expression of GDF15 mRNA",increases^expression,1,1
"2,6-Dichloroindophenol",D015086,956-48-9,GDF15,9518,"[2,6-Dichloroindophenol co-treated with NQO1 protein polymorphism] results in increased expression of GDF15 mRNA",affects^cotreatment|increases^expression,1,1
2-chloro-5-nitrobenzanilide,C457499,,GDF15,9518,[2-chloro-5-nitrobenzanilide results in decreased activity of PPARG protein] inhibits the reaction [9-deoxy-delta-9-prostaglandin D2 results in increased expression of GDF15 protein],decreases^activity|decreases^reaction|increases^expression,1,1
2-ethyl-5-carboxypentyl phthalate,C051450,40809-41-4,AMH,268,2-ethyl-5-carboxypentyl phthalate results in decreased secretion of AMH protein,decreases^secretion,1,1
2-palmitoylglycerol,C114956,,GDF15,9518,2-palmitoylglycerol results in increased expression of GDF15 mRNA,increases^expression,1,1
"3,19-(2-bromobenzylidene)andrographolide",C000598422,,GDF15,9518,"[3,19-(2-bromobenzylidene)andrographolide results in decreased susceptibility to 3,19-(2-bromobenzylidene)andrographolide] which results in increased expression of GDF15 mRNA",decreases^response to substance|increases^expression,1,1
"3,3'-diindolylmethane",C016392,1968-05-4,GDF15,9518,"3,3'-diindolylmethane results in increased expression of GDF15 mRNA",increases^expression,1,1
"3,4,3',4'-tetrachlorobiphenyl",C028451,,GDF15,9518,"3,4,3',4'-tetrachlorobiphenyl affects the expression of GDF15 mRNA",affects^expression,1,1
"3,4,5,3',4'-pentachlorobiphenyl",C023035,57465-28-8,GDF15,9518,"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of GDF15 mRNA",increases^expression,1,1
3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid,C472791,,AMH,268,3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in decreased expression of AMH mRNA,decreases^expression,1,1
"4-(4-((5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid",C584509,,GDF15,9518,"4-(4-((5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl)methylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)benzoic acid affects the expression of GDF15 mRNA",affects^expression,1,1
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole,C090942,,GDF15,9518,4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Flurbiprofen results in increased expression of GDF15 protein],decreases^reaction|increases^expression,1,1
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole,C090942,,GDF15,9518,4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Ibuprofen results in increased expression of GDF15 protein],decreases^reaction|increases^expression,1,1
"4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide",C459179,,GDF15,9518,"[NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GDF15 mRNA",affects^cotreatment|increases^expression,1,1
"4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide",C459179,,GDF15,9518,"[NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GDF15 mRNA",affects^cotreatment|increases^expression,1,1
"4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide",C459179,,GDF15,9518,"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GDF15 mRNA",affects^cotreatment|increases^expression,1,1
"4-chloro-N-((4-(1,1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide",C429623,119168-77-3,GDF15,9518,"4-chloro-N-((4-(1,1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in increased expression of GDF15 mRNA",increases^expression,1,1
4-oxoretinoic acid,C002202,38030-57-8,GDF15,9518,4-oxoretinoic acid results in increased expression of GDF15 mRNA,increases^expression,1,1
"6,7-dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine",C000595015,,GDF15,9518,"6,7-dimethoxy-2-(pyrrolidin-1-yl)-N-(5-(pyrrolidin-1-yl)pentyl)quinazolin-4-amine results in increased expression of GDF15 mRNA",increases^expression,1,1
"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide",D015123,55097-80-8,GDF15,9518,"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of GDF15 mRNA",increases^expression,3,1
8-Bromo Cyclic Adenosine Monophosphate,D015124,23583-48-4,GDF15,9518,8-Bromo Cyclic Adenosine Monophosphate results in increased expression of GDF15 mRNA,increases^expression,1,1
"9,10-dihydro-9,10-dihydroxybenzo(a)pyrene",C020738,24909-09-9,GDF15,9518,"9,10-dihydro-9,10-dihydroxybenzo(a)pyrene results in increased expression of GDF15 mRNA",increases^expression,1,1
9-deoxy-delta-9-prostaglandin D2,C037112,60203-57-8,GDF15,9518,[2-chloro-5-nitrobenzanilide results in decreased activity of PPARG protein] inhibits the reaction [9-deoxy-delta-9-prostaglandin D2 results in increased expression of GDF15 protein],decreases^activity|decreases^reaction|increases^expression,1,1
9-deoxy-delta-9-prostaglandin D2,C037112,60203-57-8,GDF15,9518,9-deoxy-delta-9-prostaglandin D2 results in increased expression of GDF15 mRNA,increases^expression,1,1
9-deoxy-delta-9-prostaglandin D2,C037112,60203-57-8,GDF15,9518,9-deoxy-delta-9-prostaglandin D2 results in increased expression of GDF15 protein,increases^expression,1,1
abrine,C496492,,GDF15,9518,abrine results in increased expression of GDF15 mRNA,increases^expression,1,1
aceclofenac,C056498,89796-99-6,GDF15,9518,aceclofenac results in increased expression of GDF15 protein,increases^expression,1,1
Acetaminophen,D000082,103-90-2,AMH,268,Acetaminophen results in decreased expression of AMH mRNA,decreases^expression,1,1
Acetaminophen,D000082,103-90-2,GDF15,9518,Acetaminophen results in increased expression of GDF15 mRNA,increases^expression,1,1
Acrylamide,D020106,,GDF15,9518,Acrylamide results in increased expression of GDF15 mRNA,increases^expression,2,1
adefovir dipivoxil,C106812,142340-99-6,GDF15,9518,adefovir dipivoxil results in increased expression of GDF15 mRNA,increases^expression,1,1
Adenine,D000225,73-24-5,GDF15,9518,Adenine results in decreased expression of GDF15 mRNA,decreases^expression,1,1
Aflatoxin B1,D016604,1162-65-8,GDF15,9518,Aflatoxin B1 affects the expression of GDF15 protein,affects^expression,1,1
Aflatoxin B1,D016604,1162-65-8,GDF15,9518,[Aflatoxin B1 co-treated with beta-Naphthoflavone] results in increased expression of GDF15 protein,affects^cotreatment|increases^expression,1,1
Aflatoxin B1,D016604,1162-65-8,GDF15,9518,Aflatoxin B1 results in increased expression of GDF15 mRNA,increases^expression,6,1
Aflatoxin B1,D016604,1162-65-8,GDF15,9518,Aflatoxin B1 results in increased expression of GDF15 protein,increases^expression,1,1
Air Pollutants,D000393,,GDF15,9518,Air Pollutants analog results in increased expression of GDF15 mRNA,increases^expression,1,1
Air Pollutants,D000393,,GDF15,9518,[Air Pollutants results in increased abundance of Particulate Matter analog] which results in increased expression of GDF15 mRNA,increases^abundance|increases^expression,1,1
Air Pollutants,D000393,,GDF15,9518,[Air Pollutants results in increased abundance of Particulate Matter] which results in increased expression of GDF15 mRNA,increases^abundance|increases^expression,1,1
Aldehydes,D000447,,GDF15,9518,Aldehydes results in increased expression of GDF15 mRNA,increases^expression,1,1
Alitretinoin,D000077556,5300-03-8,GDF15,9518,Alitretinoin results in increased expression of GDF15 mRNA,increases^expression,1,1
Am 580,C068073,102121-60-8,GDF15,9518,Am 580 results in increased expression of GDF15 mRNA,increases^expression,1,1
Amiodarone,D000638,1951-25-3,GDF15,9518,Amiodarone results in increased expression of GDF15 mRNA,increases^expression,2,1
Amphotericin B,D000666,1397-89-3,GDF15,9518,Amphotericin B analog results in increased expression of GDF15 mRNA,increases^expression,1,1
Amphotericin B,D000666,1397-89-3,GDF15,9518,Amphotericin B results in increased expression of GDF15 mRNA,increases^expression,1,1
Antimycin A,D000968,642-15-9,GDF15,9518,Antimycin A results in increased expression of GDF15 mRNA,increases^expression,1,1
Arecoline,D001115,63-75-2,GDF15,9518,Arecoline results in increased expression of GDF15 mRNA,increases^expression,1,1
aristolochic acid I,C000228,313-67-7,AMH,268,aristolochic acid I results in increased expression of AMH mRNA,increases^expression,1,1
aristolochic acid I,C000228,313-67-7,GDF15,9518,aristolochic acid I results in increased expression of GDF15 mRNA,increases^expression,1,1
Arsenates,D001149,,GDF15,9518,Arsenates results in decreased expression of GDF15 mRNA,decreases^expression,1,1
Arsenic,D001151,7440-38-2,GDF15,9518,Arsenic results in decreased expression of GDF15 mRNA,decreases^expression,1,1
Arsenic Trioxide,D000077237,1327-53-3,GDF15,9518,Arsenic Trioxide results in increased expression of GDF15 mRNA,increases^expression,4,1
arsenite,C015001,15502-74-6,GDF15,9518,arsenite promotes the reaction [G3BP1 protein binds to GDF15 mRNA],affects^binding|increases^reaction,1,1
"Asbestos, Amphibole",D017636,,GDF15,9518,"Asbestos, Amphibole affects the expression of GDF15 protein",affects^expression,1,1
"Asbestos, Crocidolite",D017638,12001-28-4,GDF15,9518,"Asbestos, Crocidolite affects the expression of GDF15 mRNA",affects^expression,1,1
"Asbestos, Crocidolite",D017638,12001-28-4,GDF15,9518,"Asbestos, Crocidolite results in increased expression of GDF15 mRNA",increases^expression,1,1
"Asbestos, Serpentine",D017632,,GDF15,9518,"Asbestos, Serpentine results in increased expression of GDF15 mRNA",increases^expression,1,1
Aspirin,D001241,50-78-2,GDF15,9518,Aspirin results in increased expression of GDF15 mRNA,increases^expression,1,1
Aspirin,D001241,50-78-2,GDF15,9518,Aspirin results in increased expression of GDF15 protein,increases^expression,1,1
Atrazine,D001280,1912-24-9,GDF15,9518,Atrazine results in increased expression of GDF15 mRNA,increases^expression,1,1
aurin,C017037,603-45-2,GDF15,9518,aurin results in increased expression of GDF15 mRNA,increases^expression,1,1
Azathioprine,D001379,446-86-6,GDF15,9518,Azathioprine results in increased expression of GDF15 mRNA,increases^expression,1,1
azoxystrobin,C087670,131860-33-8,GDF15,9518,azoxystrobin results in increased expression of GDF15 mRNA,increases^expression,1,1
Benzo(a)pyrene,D001564,50-32-8,AMH,268,Benzo(a)pyrene results in increased methylation of AMH 5' UTR,increases^methylation,1,1
Benzo(a)pyrene,D001564,50-32-8,GDF15,9518,Benzo(a)pyrene results in increased expression of GDF15 mRNA,increases^expression,10,1
beta-hydroxy simvastatin acid,C483161,,GDF15,9518,beta-hydroxy simvastatin acid affects the expression of GDF15 mRNA,affects^expression,1,1
beta-lapachone,C014638,,GDF15,9518,beta-lapachone results in increased expression of GDF15 mRNA,increases^expression,1,1
beta-methylcholine,C044887,7562-87-0,AMH,268,beta-methylcholine affects the expression of AMH mRNA,affects^expression,1,1
beta-Naphthoflavone,D019324,6051-87-2,GDF15,9518,[Aflatoxin B1 co-treated with beta-Naphthoflavone] results in increased expression of GDF15 protein,affects^cotreatment|increases^expression,1,1
beta-Naphthoflavone,D019324,6051-87-2,GDF15,9518,beta-Naphthoflavone results in decreased expression of GDF15 mRNA,decreases^expression,1,1
beta-Naphthoflavone,D019324,6051-87-2,GDF15,9518,beta-Naphthoflavone results in increased expression of GDF15 mRNA,increases^expression,1,1
beta-Naphthoflavone,D019324,6051-87-2,GDF15,9518,beta-Naphthoflavone results in increased expression of GDF15 protein,increases^expression,1,1
bisphenol A,C006780,80-05-7,AMH,268,bisphenol A results in decreased expression of AMH mRNA,decreases^expression,1,1
bisphenol A,C006780,80-05-7,AMH,268,bisphenol A results in increased expression of AMH mRNA,increases^expression,1,1
bisphenol A,C006780,80-05-7,GDF15,9518,bisphenol A affects the expression of GDF15 mRNA,affects^expression,2,1
bisphenol A,C006780,80-05-7,GDF15,9518,bisphenol A results in increased expression of GDF15 mRNA,increases^expression,4,1
bisphenol A,C006780,80-05-7,GDF15,9518,bisphenol A results in increased secretion of GDF15 protein,increases^secretion,1,1
bisphenol AF,C583074,,GDF15,9518,bisphenol AF results in increased expression of GDF15 protein,increases^expression,1,1
bisphenol S,C543008,,GDF15,9518,[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of GDF15 mRNA,affects^cotreatment|increases^expression,1,1
Bortezomib,D000069286,,GDF15,9518,[BRCA1 mutant form results in increased susceptibility to Bortezomib] which results in increased expression of GDF15 mRNA,increases^expression|increases^response to substance,1,1
bromoacetate,C016274,68-10-0,GDF15,9518,bromoacetate results in increased expression of GDF15 mRNA,increases^expression,1,1
butyraldehyde,C018475,123-72-8,AMH,268,butyraldehyde results in decreased expression of AMH mRNA,decreases^expression,1,1
butyraldehyde,C018475,123-72-8,GDF15,9518,butyraldehyde results in increased expression of GDF15 mRNA,increases^expression,1,1
Cadmium,D002104,7440-43-9,GDF15,9518,[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of GDF15 mRNA,increases^abundance|increases^expression,1,1
Cadmium Chloride,D019256,10108-64-2,AMH,268,Cadmium Chloride results in increased expression of AMH mRNA,increases^expression,1,1
Cadmium Chloride,D019256,10108-64-2,GDF15,9518,Cadmium Chloride results in decreased expression of GDF15 mRNA,decreases^expression,1,1
Cadmium Chloride,D019256,10108-64-2,GDF15,9518,[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of GDF15 mRNA,increases^abundance|increases^expression,1,1
Cadmium Chloride,D019256,10108-64-2,GDF15,9518,Cadmium Chloride results in increased expression of GDF15 mRNA,increases^expression,3,1
Cadmium Chloride,D019256,10108-64-2,GDF15,9518,[sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of GDF15 mRNA,affects^cotreatment|decreases^expression,1,1
Calcitriol,D002117,32222-06-3,GDF15,9518,Calcitriol results in increased expression of GDF15 mRNA,increases^expression,2,1
Calcitriol,D002117,32222-06-3,GDF15,9518,Calcitriol results in increased expression of GDF15 protein,increases^expression,1,1
Camptothecin,D002166,7689-03-4,GDF15,9518,Camptothecin results in increased expression of GDF15 mRNA,increases^expression,1,1
Cannabidiol,D002185,13956-29-1,GDF15,9518,Cannabidiol results in increased expression of GDF15 mRNA,increases^expression,2,1
Cannabidiol,D002185,13956-29-1,GDF15,9518,[Dronabinol co-treated with Cannabidiol] results in increased expression of GDF15 mRNA,affects^cotreatment|increases^expression,1,1
Capsaicin,D002211,404-86-4,GDF15,9518,ATF3 mutant form inhibits the reaction [Capsaicin results in increased expression of GDF15 mRNA],decreases^reaction|increases^expression,1,1
Capsaicin,D002211,404-86-4,GDF15,9518,Capsaicin results in increased expression of GDF15 mRNA,increases^expression,1,1
Capsaicin,D002211,404-86-4,GDF15,9518,Capsaicin results in increased phosphorylation of GDF15 protein,increases^phosphorylation,1,1
Capsaicin,D002211,404-86-4,GDF15,9518,CEBPB mutant form inhibits the reaction [Capsaicin results in increased expression of GDF15 mRNA],decreases^reaction|increases^expression,1,1
Capsaicin,D002211,404-86-4,GDF15,9518,[CEBPB protein binds to GDF15 promoter] promotes the reaction [Capsaicin results in increased expression of GDF15 mRNA],affects^binding|increases^expression|increases^reaction,1,1
Capsaicin,D002211,404-86-4,GDF15,9518,CEBPB protein promotes the reaction [Capsaicin results in increased expression of GDF15 mRNA],increases^expression|increases^reaction,1,1
Capsaicin,D002211,404-86-4,GDF15,9518,GSK3B mutant form inhibits the reaction [Capsaicin results in increased expression of GDF15 mRNA],decreases^reaction|increases^expression,1,1
Carbamazepine,D002220,298-46-4,AMH,268,[Carbamazepine co-treated with Lamotrigine] results in increased secretion of AMH protein,affects^cotreatment|increases^secretion,1,1
Carbamazepine,D002220,298-46-4,AMH,268,Carbamazepine results in decreased expression of AMH mRNA,decreases^expression,1,1
Carbamazepine,D002220,298-46-4,AMH,268,Carbamazepine results in increased expression of AMH protein,increases^expression,1,1
Carbamazepine,D002220,298-46-4,GDF15,9518,Carbamazepine affects the expression of GDF15 mRNA,affects^expression,1,1
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone,D002259,370-86-5,GDF15,9518,Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in increased expression of GDF15 mRNA,increases^expression,1,1
Carmustine,D002330,154-93-8,AMH,268,Carmustine results in decreased expression of AMH mRNA,decreases^expression,1,1
CD 437,C099555,,AMH,268,CD 437 results in decreased expression of AMH mRNA,decreases^expression,1,1
celastrol,C050414,,GDF15,9518,celastrol results in increased expression of GDF15 mRNA,increases^expression,1,1
Celecoxib,D000068579,,GDF15,9518,[Celecoxib co-treated with Octreotide] results in increased expression of GDF15 mRNA,affects^cotreatment|increases^expression,1,1
Celecoxib,D000068579,,GDF15,9518,Celecoxib results in increased expression of GDF15,increases^expression,1,1
Celecoxib,D000068579,,GDF15,9518,Celecoxib results in increased expression of GDF15 mRNA,increases^expression,3,1
Celecoxib,D000068579,,GDF15,9518,GSK3B mutant form inhibits the reaction [Celecoxib results in increased expression of GDF15],decreases^reaction|increases^expression,1,1
Celecoxib,D000068579,,GDF15,9518,PTGS2 protein affects the reaction [Celecoxib results in increased expression of GDF15 mRNA],affects^reaction|increases^expression,1,1
Celecoxib,D000068579,,GDF15,9518,SB 216763 inhibits the reaction [Celecoxib results in increased expression of GDF15],decreases^reaction|increases^expression,1,1
chloroacetaldehyde,C004656,107-20-0,GDF15,9518,chloroacetaldehyde results in increased expression of GDF15 mRNA,increases^expression,1,1
chloropicrin,C100187,76-06-2,GDF15,9518,chloropicrin results in increased expression of GDF15 mRNA,increases^expression,1,1
chromic oxide,C023600,1308-38-9,GDF15,9518,[sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of GDF15 mRNA,affects^cotreatment|decreases^expression,1,1
chromium hexavalent ion,C074702,18540-29-9,GDF15,9518,[zinc chromate results in increased abundance of chromium hexavalent ion] which results in increased expression of GDF15 mRNA,increases^abundance|increases^expression,1,1
chromous chloride,C017133,10049-05-5,GDF15,9518,[sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of GDF15 mRNA,affects^cotreatment|decreases^expression,1,1
Cidofovir,D000077404,113852-37-2,GDF15,9518,Cidofovir results in increased expression of GDF15 mRNA,increases^expression,1,1
Cisplatin,D002945,15663-27-1,AMH,268,Cisplatin results in decreased expression of AMH mRNA,decreases^expression,1,1
Cisplatin,D002945,15663-27-1,GDF15,9518,Cisplatin affects the expression of GDF15 mRNA,affects^expression,1,1
Cisplatin,D002945,15663-27-1,GDF15,9518,Cisplatin inhibits the reaction [Piroxicam results in decreased expression of GDF15 mRNA],decreases^expression|decreases^reaction,1,1
Cisplatin,D002945,15663-27-1,GDF15,9518,Cisplatin results in increased expression of GDF15 mRNA,increases^expression,5,1
Cisplatin,D002945,15663-27-1,GDF15,9518,Folic Acid affects the reaction [Cisplatin affects the expression of GDF15 mRNA],affects^expression|affects^reaction,1,1
Citrinin,D002953,518-75-2,GDF15,9518,Citrinin results in increased expression of GDF15 protein,increases^expression,1,1
Clodronic Acid,D004002,10596-23-3,GDF15,9518,Clodronic Acid results in decreased expression of GDF15 mRNA,decreases^expression,1,1
clothianidin,C480342,,GDF15,9518,clothianidin results in increased expression of GDF15 mRNA,increases^expression,1,1
Clozapine,D003024,5786-21-0,GDF15,9518,Clozapine results in increased expression of GDF15 protein,increases^expression,1,1
Cobalt,D003035,7440-48-4,GDF15,9518,[tungsten carbide binds to Cobalt] which affects the expression of GDF15 mRNA,affects^binding|affects^expression,1,1
cobaltous chloride,C018021,7646-79-9,GDF15,9518,cobaltous chloride results in decreased expression of GDF15 mRNA,decreases^expression,1,1
cobaltous chloride,C018021,7646-79-9,GDF15,9518,cobaltous chloride results in increased expression of GDF15 mRNA,increases^expression,1,1
Colchicine,D003078,64-86-8,GDF15,9518,Colchicine results in decreased expression of GDF15 mRNA,decreases^expression,1,1
Copper Sulfate,D019327,7758-98-7,GDF15,9518,Copper Sulfate results in increased expression of GDF15 mRNA,increases^expression,1,1
cordycepin,C058120,73-03-0,GDF15,9518,cordycepin affects the expression of GDF15 mRNA,affects^expression,1,1
corosolic acid,C113861,,GDF15,9518,corosolic acid results in increased expression of GDF15 mRNA,increases^expression,1,1
Coumestrol,D003375,479-13-0,GDF15,9518,"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of GDF15 mRNA",affects^cotreatment|decreases^expression,1,1
Coumestrol,D003375,479-13-0,GDF15,9518,Coumestrol results in decreased expression of GDF15 mRNA,decreases^expression,1,1
CP 31398,C402665,,GDF15,9518,CP 31398 results in increased expression of GDF15 mRNA,increases^expression,1,1
cryptolepine,C024015,480-26-2,GDF15,9518,cryptolepine results in increased expression of GDF15 mRNA,increases^expression,1,1
cupric oxide,C030973,1317-38-0,GDF15,9518,cupric oxide results in increased expression of GDF15 mRNA,increases^expression,1,1
Cycloheximide,D003513,66-81-9,GDF15,9518,Cycloheximide inhibits the reaction [trichostatin A affects the expression of GDF15 mRNA],affects^expression|decreases^reaction,1,1
Cycloheximide,D003513,66-81-9,GDF15,9518,Cycloheximide inhibits the reaction [trichostatin A affects the expression of GDF15 protein],affects^expression|decreases^reaction,1,1
Cycloheximide,D003513,66-81-9,GDF15,9518,Cycloheximide inhibits the reaction [Troglitazone results in increased expression of GDF15 mRNA],decreases^reaction|increases^expression,1,1
Cyclosporine,D016572,59865-13-3,GDF15,9518,Cyclosporine results in increased expression of GDF15 mRNA,increases^expression,7,1
cylindrospermopsin,C089595,143545-90-8,GDF15,9518,cylindrospermopsin results in increased expression of GDF15 mRNA,increases^expression,2,1
Dactinomycin,D003609,50-76-0,GDF15,9518,[Dactinomycin co-treated with nutlin 3] results in increased expression of GDF15 mRNA,affects^cotreatment|increases^expression,1,1
Dactinomycin,D003609,50-76-0,GDF15,9518,Dactinomycin inhibits the reaction [Resveratrol results in increased expression of GDF15 mRNA],decreases^reaction|increases^expression,1,1
Dactinomycin,D003609,50-76-0,GDF15,9518,Dactinomycin results in increased expression of GDF15 mRNA,increases^expression,1,1
darinaparsin,C515055,,GDF15,9518,darinaparsin results in decreased expression of GDF15 mRNA,decreases^expression,1,1
darinaparsin,C515055,,GDF15,9518,Oxygen deficiency inhibits the reaction [darinaparsin results in decreased expression of GDF15 mRNA],decreases^expression|decreases^reaction,1,1
Daunorubicin,D003630,20830-81-3,GDF15,9518,Daunorubicin results in increased expression of GDF15 mRNA,increases^expression,2,1
decabromobiphenyl ether,C010902,1163-19-5,GDF15,9518,decabromobiphenyl ether results in increased expression of GDF15 protein,increases^expression,1,1
Decitabine,D000077209,2353-33-5,AMH,268,Decitabine results in decreased expression of AMH mRNA,decreases^expression,1,1
Decitabine,D000077209,2353-33-5,AMH,268,TP53 protein affects the reaction [Decitabine results in decreased expression of AMH mRNA],affects^reaction|decreases^expression,1,1
Decitabine,D000077209,2353-33-5,GDF15,9518,Decitabine affects the expression of GDF15 mRNA,affects^expression,2,1
Decitabine,D000077209,2353-33-5,GDF15,9518,Decitabine promotes the reaction [[trichostatin A affects the methylation of GDF15 promoter] which affects the expression of GDF15 mRNA],affects^expression|affects^methylation|increases^reaction,1,1
Decitabine,D000077209,2353-33-5,GDF15,9518,Decitabine promotes the reaction [[trichostatin A affects the methylation of GDF15 promoter] which affects the expression of GDF15 protein],affects^expression|affects^methylation|increases^reaction,1,1
deguelin,C107676,522-17-8,GDF15,9518,deguelin results in increased expression of GDF15 mRNA,increases^expression,1,1
Demecolcine,D003703,477-30-5,GDF15,9518,Demecolcine results in increased expression of GDF15 mRNA,increases^expression,1,1
deoxynivalenol,C007262,51481-10-8,GDF15,9518,deoxynivalenol results in increased expression of GDF15 protein,increases^expression,1,1
Dexamethasone,D003907,50-02-2,GDF15,9518,Dexamethasone results in decreased expression of GDF15 mRNA,decreases^expression,1,1
Dexamethasone,D003907,50-02-2,GDF15,9518,[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of GDF15 mRNA,affects^cotreatment|increases^expression,1,1
Dexamethasone,D003907,50-02-2,GDF15,9518,[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of GDF15 mRNA,affects^cotreatment|decreases^expression,1,1
diallyl disulfide,C028009,2179-57-9,GDF15,9518,diallyl disulfide results in increased expression of GDF15 protein,increases^expression,1,1
diallyl disulfide,C028009,2179-57-9,GDF15,9518,TP53 protein affects the reaction [diallyl disulfide results in increased expression of GDF15 protein],affects^reaction|increases^expression,1,1
Dibutyl Phthalate,D003993,84-74-2,GDF15,9518,[Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GDF15 protein,affects^cotreatment|decreases^expression,1,1
Diclofenac,D004008,15307-86-5,GDF15,9518,Diclofenac results in increased expression of GDF15 protein,increases^expression,1,1
dicrotophos,C000944,3735-78-2,GDF15,9518,dicrotophos results in increased expression of GDF15 mRNA,increases^expression,1,1
didecyldimethylammonium,C027118,20256-56-8,GDF15,9518,didecyldimethylammonium results in increased expression of GDF15 mRNA,increases^expression,1,1
Diethylhexyl Phthalate,D004051,117-81-7,GDF15,9518,Diethylhexyl Phthalate results in increased expression of GDF15 mRNA,increases^expression,1,1
diethyl maleate,C014476,141-05-9,GDF15,9518,diethyl maleate results in increased expression of GDF15 mRNA,increases^expression,1,1
Diethylnitrosamine,D004052,55-18-5,GDF15,9518,Diethylnitrosamine results in increased expression of GDF15 mRNA,increases^expression,1,1
Dihydrotestosterone,D013196,521-18-6,GDF15,9518,Dihydrotestosterone results in increased expression of GDF15 mRNA,increases^expression,1,1
Dihydroxyacetone,D004098,96-26-4,GDF15,9518,Dihydroxyacetone results in decreased expression of GDF15 mRNA,decreases^expression,1,1
dimethylarsinous acid,C472511,,GDF15,9518,dimethylarsinous acid results in increased expression of GDF15 mRNA,increases^expression,1,1
diphenylarsinic acid,C493087,,GDF15,9518,diphenylarsinic acid results in increased secretion of GDF15 protein,increases^secretion,1,1
dorsomorphin,C516138,,GDF15,9518,"[NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GDF15 mRNA",affects^cotreatment|increases^expression,1,1
dorsomorphin,C516138,,GDF15,9518,"[NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GDF15 mRNA",affects^cotreatment|increases^expression,1,1
dorsomorphin,C516138,,GDF15,9518,"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GDF15 mRNA",affects^cotreatment|increases^expression,1,1
Doxorubicin,D004317,23214-92-8,GDF15,9518,Doxorubicin results in decreased expression of GDF15 mRNA,decreases^expression,1,1
Doxorubicin,D004317,23214-92-8,GDF15,9518,Doxorubicin results in increased expression of GDF15 mRNA,increases^expression,6,1
Doxorubicin,D004317,23214-92-8,GDF15,9518,GDF15 protein results in decreased susceptibility to Doxorubicin,decreases^response to substance,1,1
Dronabinol,D013759,,AMH,268,Dronabinol results in increased expression of AMH mRNA,increases^expression,1,1
Dronabinol,D013759,,GDF15,9518,[Dronabinol co-treated with Cannabidiol] results in increased expression of GDF15 mRNA,affects^cotreatment|increases^expression,1,1
Dronabinol,D013759,,GDF15,9518,Dronabinol results in decreased expression of GDF15 mRNA,decreases^expression,1,1
Dronabinol,D013759,,GDF15,9518,Dronabinol results in increased expression of GDF15 mRNA,increases^expression,2,1
"Drugs, Chinese Herbal",D004365,,GDF15,9518,"Drugs, Chinese Herbal results in increased expression of GDF15 mRNA",increases^expression,2,1
Dust,D004391,,AMH,268,Dust results in decreased expression of AMH mRNA,decreases^expression,1,1
(E)-4-((2-N-(4-methoxybenzenesulfonyl)amino)stilbazole)1-oxide,C479799,,GDF15,9518,(E)-4-((2-N-(4-methoxybenzenesulfonyl)amino)stilbazole)1-oxide results in decreased expression of GDF15 mRNA,decreases^expression,1,1
(E)-4-((2-N-(4-methoxybenzenesulfonyl)amino)stilbazole)1-oxide,C479799,,GDF15,9518,(E)-4-((2-N-(4-methoxybenzenesulfonyl)amino)stilbazole)1-oxide results in increased expression of GDF15 mRNA,increases^expression,1,1
Endosulfan,D004726,115-29-7,GDF15,9518,[Endosulfan co-treated with Tetrachlorodibenzodioxin] results in increased expression of GDF15 mRNA,affects^cotreatment|increases^expression,1,1
entinostat,C118739,,GDF15,9518,entinostat results in increased expression of GDF15 mRNA,increases^expression,1,1
entinostat,C118739,,GDF15,9518,"[NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GDF15 mRNA",affects^cotreatment|increases^expression,1,1
epigallocatechin gallate,C045651,989-51-5,AMH,268,[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of AMH mRNA,affects^cotreatment|increases^expression,1,1
Erlotinib Hydrochloride,D000069347,,GDF15,9518,[Gemcitabine co-treated with Erlotinib Hydrochloride] affects the expression of GDF15 protein,affects^cotreatment|affects^expression,1,1
Esketamine,C000629870,,GDF15,9518,Esketamine results in increased expression of GDF15 mRNA,increases^expression,1,1
Estradiol,D004958,50-28-2,AMH,268,Estradiol results in increased expression of AMH mRNA,increases^expression,1,1
Estradiol,D004958,50-28-2,GDF15,9518,[Estradiol co-treated with Progesterone] results in decreased expression of GDF15 mRNA,affects^cotreatment|decreases^expression,1,1
Estradiol,D004958,50-28-2,GDF15,9518,[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of GDF15 mRNA,affects^cotreatment|increases^expression,1,1
Estradiol,D004958,50-28-2,GDF15,9518,[Estradiol co-treated with TGFB1 protein] results in decreased expression of GDF15 mRNA,affects^cotreatment|decreases^expression,1,1
Estradiol,D004958,50-28-2,GDF15,9518,Estradiol results in decreased expression of GDF15 mRNA,decreases^expression,1,1
Estradiol,D004958,50-28-2,GDF15,9518,Estradiol results in increased expression of GDF15 mRNA,increases^expression,5,1
Ethanol,D000431,64-17-5,GDF15,9518,Ethanol results in increased expression of GDF15 mRNA,increases^expression,1,1
Ethyl Methanesulfonate,D005020,62-50-0,GDF15,9518,Ethyl Methanesulfonate results in increased expression of GDF15 mRNA,increases^expression,2,1
Etoposide,D005047,33419-42-0,GDF15,9518,Etoposide promotes the reaction [[TP53 protein binds to GDF15 promoter] which results in increased expression of GDF15 mRNA],affects^binding|increases^expression|increases^reaction,1,1
Etoposide,D005047,33419-42-0,GDF15,9518,Etoposide results in increased expression of GDF15 mRNA,increases^expression,3,1
Etoposide,D005047,33419-42-0,GDF15,9518,Etoposide results in increased expression of GDF15 protein,increases^expression,1,1
Etoposide,D005047,33419-42-0,GDF15,9518,[Etoposide results in increased expression of TP53 protein] which results in increased expression of GDF15 protein,increases^expression,1,1
Fenofibrate,D011345,49562-28-9,GDF15,9518,Fenofibrate results in increased expression of GDF15 mRNA,increases^expression,1,1
fenpyroximate,C415144,134098-61-6,GDF15,9518,fenpyroximate results in increased expression of GDF15 mRNA,increases^expression,1,1
Fenretinide,D017313,65646-68-6,GDF15,9518,Fenretinide results in increased expression of GDF15 mRNA,increases^expression,2,1
Fenretinide,D017313,65646-68-6,GDF15,9518,Fenretinide results in increased expression of GDF15 protein,increases^expression,1,1
ferrous chloride,C029451,7758-94-3,AMH,268,ferrous chloride results in decreased expression of AMH mRNA,decreases^expression,1,1
ferrous chloride,C029451,7758-94-3,GDF15,9518,ferrous chloride results in increased expression of GDF15 mRNA,increases^expression,1,1
fludarabine,C024352,21679-14-1,GDF15,9518,fludarabine results in increased expression of GDF15 mRNA,increases^expression,1,1
Fluorocarbons,D005466,,GDF15,9518,Fluorocarbons affects the expression of GDF15 protein,affects^expression,1,1
Fluorouracil,D005472,51-21-8,GDF15,9518,Fluorouracil results in increased expression of GDF15 mRNA,increases^expression,2,1
Fluorouracil,D005472,51-21-8,GDF15,9518,Fluorouracil results in increased expression of GDF15 protein,increases^expression,1,1
Fluorouracil,D005472,51-21-8,GDF15,9518,TP53 protein affects the reaction [Fluorouracil results in increased expression of GDF15 mRNA],affects^reaction|increases^expression,1,1
Flurbiprofen,D005480,5104-49-4,GDF15,9518,4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Flurbiprofen results in increased expression of GDF15 protein],decreases^reaction|increases^expression,1,1
Flurbiprofen,D005480,5104-49-4,GDF15,9518,Flurbiprofen results in increased expression of GDF15 protein,increases^expression,1,1
Flurbiprofen,D005480,5104-49-4,GDF15,9518,MAPK14 protein promotes the reaction [Flurbiprofen results in increased expression of GDF15 protein],increases^expression|increases^reaction,1,1
Flurbiprofen,D005480,5104-49-4,GDF15,9518,NGFR protein promotes the reaction [Flurbiprofen results in increased expression of GDF15 protein],increases^expression|increases^reaction,1,1
Folic Acid,D005492,59-30-3,GDF15,9518,Folic Acid affects the reaction [Cisplatin affects the expression of GDF15 mRNA],affects^expression|affects^reaction,1,1
Formaldehyde,D005557,50-00-0,GDF15,9518,Formaldehyde results in decreased expression of GDF15 mRNA,decreases^expression,1,1
Formaldehyde,D005557,50-00-0,GDF15,9518,Formaldehyde results in increased expression of GDF15 mRNA,increases^expression,1,1
Gasoline,D005742,,GDF15,9518,[[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of GDF15 mRNA,affects^cotreatment|increases^abundance|increases^expression,1,1
Gasoline,D005742,,GDF15,9518,[Gasoline results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of GDF15 mRNA,affects^cotreatment|increases^abundance|increases^expression,1,1
gedunin,C106014,2753-30-2,GDF15,9518,gedunin results in increased expression of GDF15 mRNA,increases^expression,1,1
Gemcitabine,D000093542,,GDF15,9518,[Gemcitabine co-treated with Erlotinib Hydrochloride] affects the expression of GDF15 protein,affects^cotreatment|affects^expression,1,1
Genistein,D019833,446-72-0,GDF15,9518,Genistein results in decreased expression of GDF15 mRNA,decreases^expression,1,1
Genistein,D019833,446-72-0,GDF15,9518,Genistein results in increased expression of GDF15 mRNA,increases^expression,2,1
gingerol,C007845,1391-73-7,GDF15,9518,gingerol results in increased expression of GDF15 mRNA,increases^expression,1,1
gingerol,C007845,1391-73-7,GDF15,9518,gingerol results in increased expression of GDF15 protein,increases^expression,1,1
gingerol,C007845,1391-73-7,GDF15,9518,GSK3B protein affects the reaction [gingerol results in increased expression of GDF15 protein],affects^reaction|increases^expression,1,1
gingerol,C007845,1391-73-7,GDF15,9518,PRKCE protein affects the reaction [gingerol results in increased expression of GDF15 protein],affects^reaction|increases^expression,1,1
gingerol,C007845,1391-73-7,GDF15,9518,Ro 31-8220 inhibits the reaction [gingerol results in increased expression of GDF15 protein],decreases^reaction|increases^expression,1,1
Glucose,D005947,50-99-7,GDF15,9518,Glucose results in decreased expression of GDF15 mRNA,decreases^expression,1,1
Glucose,D005947,50-99-7,GDF15,9518,Glucose results in increased expression of GDF15 mRNA,increases^expression,1,1
Glupearl 19S,C000606994,,GDF15,9518,Glupearl 19S results in increased expression of GDF15 mRNA,increases^expression,1,1
Gold Compounds,D017612,,AMH,268,Gold Compounds results in increased expression of AMH mRNA,increases^expression,1,1
gossypol acetic acid,C028178,12542-36-8,GDF15,9518,gossypol acetic acid results in increased expression of GDF15 protein,increases^expression,1,1
hexabrominated diphenyl ether 153,C517828,,GDF15,9518,hexabrominated diphenyl ether 153 results in increased expression of GDF15 protein,increases^expression,1,1
Hydrogen Peroxide,D006861,7722-84-1,GDF15,9518,Hydrogen Peroxide affects the expression of GDF15 mRNA,affects^expression,1,1
Hydrogen Peroxide,D006861,7722-84-1,GDF15,9518,[Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of GDF15 protein,affects^cotreatment|decreases^expression,1,1
Hydrogen Peroxide,D006861,7722-84-1,GDF15,9518,Hydrogen Peroxide results in increased expression of GDF15,increases^expression,1,1
Hydrogen Peroxide,D006861,7722-84-1,GDF15,9518,Hydrogen Peroxide results in increased expression of GDF15 mRNA,increases^expression,3,1
Hydrogen Peroxide,D006861,7722-84-1,GDF15,9518,Hydrogen Peroxide results in increased expression of GDF15 protein,increases^expression,1,1
hydroquinone,C031927,123-31-9,GDF15,9518,hydroquinone results in increased expression of GDF15 mRNA,increases^expression,2,1
hydroxyhydroquinone,C013038,533-73-3,GDF15,9518,hydroxyhydroquinone results in increased expression of GDF15 mRNA,increases^expression,1,1
Hydroxyurea,D006918,127-07-1,GDF15,9518,Hydroxyurea results in increased expression of GDF15 mRNA,increases^expression,1,1
Ibuprofen,D007052,15687-27-1,GDF15,9518,4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Ibuprofen results in increased expression of GDF15 protein],decreases^reaction|increases^expression,1,1
Ibuprofen,D007052,15687-27-1,GDF15,9518,Ibuprofen results in increased expression of GDF15 mRNA,increases^expression,1,1
Ibuprofen,D007052,15687-27-1,GDF15,9518,Ibuprofen results in increased expression of GDF15 protein,increases^expression,2,1
Ibuprofen,D007052,15687-27-1,GDF15,9518,MAPK14 protein promotes the reaction [Ibuprofen results in increased expression of GDF15 protein],increases^expression|increases^reaction,1,1
Ibuprofen,D007052,15687-27-1,GDF15,9518,NGFR protein promotes the reaction [Ibuprofen results in increased expression of GDF15 protein],increases^expression|increases^reaction,1,1
ICG 001,C492448,,GDF15,9518,ICG 001 results in increased expression of GDF15 mRNA,increases^expression,1,1
Ifosfamide,D007069,3778-73-2,GDF15,9518,Ifosfamide results in increased expression of GDF15 mRNA,increases^expression,1,1
imidazopyrazole,C026262,251-80-9,GDF15,9518,imidazopyrazole analog results in increased expression of GDF15 mRNA,increases^expression,1,1
indole-3-carbinol,C016517,700-06-1,GDF15,9518,[indole-3-carbinol co-treated with Resveratrol] results in increased expression of GDF15,affects^cotreatment|increases^expression,1,1
indole-3-carbinol,C016517,700-06-1,GDF15,9518,indole-3-carbinol results in increased expression of GDF15,increases^expression,1,1
Indomethacin,D007213,53-86-1,GDF15,9518,GDF15 protein results in decreased susceptibility to Indomethacin,decreases^response to substance,1,1
Indomethacin,D007213,53-86-1,GDF15,9518,Indomethacin results in increased expression of GDF15 mRNA,increases^expression,3,1
Indomethacin,D007213,53-86-1,GDF15,9518,Indomethacin results in increased expression of GDF15 protein,increases^expression,4,1
Indomethacin,D007213,53-86-1,GDF15,9518,[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of GDF15 mRNA,affects^cotreatment|increases^expression,1,1
Indomethacin,D007213,53-86-1,GDF15,9518,[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of GDF15 mRNA,affects^cotreatment|decreases^expression,1,1
Irinotecan,D000077146,,GDF15,9518,Irinotecan metabolite results in increased expression of GDF15 mRNA,increases^expression,1,1
Irinotecan,D000077146,,GDF15,9518,Irinotecan results in increased expression of GDF15 mRNA,increases^expression,1,1
Isotretinoin,D015474,4759-48-2,GDF15,9518,Isotretinoin results in increased expression of GDF15 mRNA,increases^expression,1,1
Ivermectin,D007559,70288-86-7,GDF15,9518,Ivermectin results in decreased expression of GDF15 protein,decreases^expression,1,1
jasplakinolide,C057531,102396-24-7,GDF15,9518,jasplakinolide results in increased expression of GDF15 mRNA,increases^expression,1,1
jasplakinolide,C057531,102396-24-7,GDF15,9518,jasplakinolide results in increased expression of GDF15 protein,increases^expression,1,1
jasplakinolide,C057531,102396-24-7,GDF15,9518,[SB 203580 co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] inhibits the reaction [jasplakinolide results in increased expression of GDF15 protein],affects^cotreatment|decreases^reaction|increases^expression,1,1
(+)-JQ1 compound,C561695,,GDF15,9518,(+)-JQ1 compound results in decreased expression of GDF15 mRNA,decreases^expression,1,1
K 7174,C410337,,GDF15,9518,K 7174 results in increased expression of GDF15 mRNA,increases^expression,1,1
Ketoconazole,D007654,65277-42-1,AMH,268,Ketoconazole results in increased expression of AMH protein,increases^expression,1,1
Lamotrigine,D000077213,84057-84-1,AMH,268,[Carbamazepine co-treated with Lamotrigine] results in increased secretion of AMH protein,affects^cotreatment|increases^secretion,1,1
lasiocarpine,C005136,303-34-4,GDF15,9518,lasiocarpine results in increased expression of GDF15 mRNA,increases^expression,2,1
latrunculin B,C037068,76343-94-7,GDF15,9518,latrunculin B results in increased expression of GDF15 mRNA,increases^expression,1,1
latrunculin B,C037068,76343-94-7,GDF15,9518,latrunculin B results in increased expression of GDF15 protein,increases^expression,1,1
latrunculin B,C037068,76343-94-7,GDF15,9518,[SB 203580 co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] inhibits the reaction [latrunculin B results in increased expression of GDF15 protein],affects^cotreatment|decreases^reaction|increases^expression,1,1
lead acetate,C008261,301-04-2,GDF15,9518,lead acetate results in increased expression of GDF15 mRNA,increases^expression,1,1
lead acetate,C008261,301-04-2,GDF15,9518,[sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of GDF15 mRNA,affects^cotreatment|decreases^expression,1,1
Leflunomide,D000077339,75706-12-6,GDF15,9518,Leflunomide results in increased expression of GDF15 mRNA,increases^expression,1,1
LG 100815,C533894,,GDF15,9518,LG 100815 results in increased expression of GDF15 mRNA,increases^expression,1,1
Lipopolysaccharides,D008070,,GDF15,9518,[NAT10 protein affects the susceptibility to Lipopolysaccharides] which affects the expression of GDF15 mRNA,affects^expression|affects^response to substance,1,1
Lipopolysaccharides,D008070,,GDF15,9518,"[S-(1,2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of GDF15 mRNA",affects^cotreatment|decreases^expression,1,1
Lucanthone,D008154,479-50-5,GDF15,9518,Lucanthone results in increased expression of GDF15 mRNA,increases^expression,1,1
Luteolin,D047311,491-70-3,GDF15,9518,Luteolin inhibits the reaction [SOX4 protein binds to GDF15 promoter],affects^binding|decreases^reaction,1,1
Luteolin,D047311,491-70-3,GDF15,9518,Luteolin results in decreased expression of GDF15 mRNA,decreases^expression,1,1
Luteolin,D047311,491-70-3,GDF15,9518,SOX4 protein inhibits the reaction [Luteolin inhibits the reaction [SOX4 protein binds to GDF15 promoter]],affects^binding|decreases^reaction,1,1
Luteolin,D047311,491-70-3,GDF15,9518,SOX4 protein inhibits the reaction [Luteolin results in decreased expression of GDF15 mRNA],decreases^expression|decreases^reaction,1,1
Manganese,D008345,7439-96-5,GDF15,9518,Manganese results in increased expression of GDF15 mRNA,increases^expression,1,1
manganese chloride,C025340,7773-01-5,GDF15,9518,manganese chloride results in increased expression of GDF15 mRNA,increases^expression,1,1
mercuric bromide,C042720,7789-47-1,GDF15,9518,mercuric bromide results in increased expression of GDF15 mRNA,increases^expression,1,1
mercuric bromide,C042720,7789-47-1,GDF15,9518,"[NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GDF15 mRNA",affects^cotreatment|increases^expression,1,1
"Metals, Heavy",D019216,,GDF15,9518,"Metals, Heavy results in decreased expression of GDF15 mRNA",decreases^expression,1,1
Methamphetamine,D008694,537-46-2,GDF15,9518,Methamphetamine results in increased expression of GDF15 mRNA,increases^expression,1,1
methyleugenol,C005223,93-15-2,GDF15,9518,methyleugenol results in increased expression of GDF15 mRNA,increases^expression,2,1
methylmercuric chloride,C004925,115-09-3,GDF15,9518,methylmercuric chloride results in increased expression of GDF15 mRNA,increases^expression,2,1
Methylmercury Compounds,D008767,,GDF15,9518,Methylmercury Compounds results in increased expression of GDF15 mRNA,increases^expression,1,1
Methyl Methanesulfonate,D008741,66-27-3,GDF15,9518,Methyl Methanesulfonate results in increased expression of GDF15 mRNA,increases^expression,2,1
Methylnitronitrosoguanidine,D008769,70-25-7,GDF15,9518,Methylnitronitrosoguanidine results in increased expression of GDF15 mRNA,increases^expression,2,1
methylparaben,C015358,99-76-3,GDF15,9518,methylparaben results in increased expression of GDF15 mRNA,increases^expression,1,1
Metribolone,D015741,965-93-5,AMH,268,AMH protein inhibits the reaction [Metribolone results in increased expression of KLK3 mRNA],decreases^reaction|increases^expression,1,1
Metribolone,D015741,965-93-5,GDF15,9518,Metribolone results in increased expression of GDF15 mRNA,increases^expression,1,1
Mitomycin,D016685,50-07-7,GDF15,9518,Mitomycin results in increased expression of GDF15 mRNA,increases^expression,1,1
Mitotane,D008939,53-19-0,GDF15,9518,Mitotane results in increased expression of GDF15 mRNA,increases^expression,1,1
Mitoxantrone,D008942,65271-80-9,GDF15,9518,Mitoxantrone results in increased expression of GDF15 mRNA,increases^expression,2,1
mono-(2-ethylhexyl)phthalate,C016599,4376-20-9,AMH,268,mono-(2-ethylhexyl)phthalate results in decreased expression of AMH mRNA,decreases^expression,1,1
mono-(2-ethylhexyl)phthalate,C016599,4376-20-9,GDF15,9518,mono-(2-ethylhexyl)phthalate results in increased expression of GDF15 mRNA,increases^expression,1,1
monoethyl phthalate,C581825,,AMH,268,monoethyl phthalate results in increased secretion of AMH protein,increases^secretion,1,1
monomethylarsonous acid,C406082,,GDF15,9518,[monomethylarsonous acid affects the acetylation of H3-4 protein] which affects the methylation of GDF15 promoter,affects^acetylation|affects^methylation,1,1
monomethylarsonous acid,C406082,,GDF15,9518,monomethylarsonous acid results in decreased expression of GDF15 mRNA,decreases^expression,1,1
MOPP protocol,C014553,,AMH,268,MOPP protocol results in decreased expression of AMH protein,decreases^expression,1,1
Mustard Gas,D009151,505-60-2,GDF15,9518,Mustard Gas results in increased expression of GDF15 mRNA,increases^expression,1,1
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide,C080955,123653-11-2,GDF15,9518,N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in increased expression of GDF15 protein,increases^expression,1,1
"Nanotubes, Carbon",D037742,,GDF15,9518,"Nanotubes, Carbon results in increased expression of GDF15 mRNA",increases^expression,1,1
naphthenic acid,C046170,1338-24-5,GDF15,9518,naphthenic acid results in increased expression of GDF15 mRNA,increases^expression,1,1
naphthenic acid,C046170,1338-24-5,GDF15,9518,[Water Pollutants results in increased abundance of naphthenic acid] which results in increased expression of GDF15 mRNA,increases^abundance|increases^expression,1,1
naphthenic acid,C046170,1338-24-5,GDF15,9518,[Water Pollutants results in increased abundance of naphthenic acid] which results in increased secretion of GDF15 protein,increases^abundance|increases^secretion,1,1
Naphthoquinones,D009285,,GDF15,9518,Naphthoquinones results in increased expression of GDF15 mRNA,increases^expression,1,1
N-caproylsphingosine,C101954,,GDF15,9518,N-caproylsphingosine results in increased expression of GDF15 mRNA,increases^expression,1,1
N-caproylsphingosine,C101954,,GDF15,9518,N-caproylsphingosine results in increased expression of GDF15 protein,increases^expression,1,1
netoglitazone,C115174,,GDF15,9518,KLF4 mRNA affects the reaction [netoglitazone results in increased expression of GDF15 protein],affects^reaction|increases^expression,1,1
netoglitazone,C115174,,GDF15,9518,netoglitazone results in increased expression of GDF15 mRNA,increases^expression,1,1
netoglitazone,C115174,,GDF15,9518,netoglitazone results in increased expression of GDF15 protein,increases^expression,1,1
nickel chloride,C022838,7718-54-9,GDF15,9518,nickel chloride results in increased expression of GDF15 mRNA,increases^expression,1,1
nickel sulfate,C029938,7786-81-4,GDF15,9518,nickel sulfate results in increased expression of GDF15 mRNA,increases^expression,1,1
Niclosamide,D009534,50-65-7,GDF15,9518,Niclosamide results in increased expression of GDF15 mRNA,increases^expression,1,1
nivalenol,C038405,23282-20-4,GDF15,9518,nivalenol results in increased expression of GDF15 protein,increases^expression,1,1
N-Nitrosopyrrolidine,D009242,930-55-2,GDF15,9518,N-Nitrosopyrrolidine results in increased expression of GDF15 mRNA,increases^expression,2,1
NSC305787,C570896,,GDF15,9518,NSC305787 results in increased expression of GDF15 mRNA,increases^expression,1,1
NSC668394,C570897,,GDF15,9518,NSC668394 results in increased expression of GDF15 mRNA,increases^expression,1,1
nutlin 3,C482205,,GDF15,9518,[Dactinomycin co-treated with nutlin 3] results in increased expression of GDF15 mRNA,affects^cotreatment|increases^expression,1,1
nutlin 3,C482205,,GDF15,9518,nutlin 3 results in increased expression of GDF15 mRNA,increases^expression,2,1
"octa-2,4,6-trienoic acid",C062198,5205-32-3,GDF15,9518,"octa-2,4,6-trienoic acid results in increased expression of GDF15 mRNA",increases^expression,1,1
Octreotide,D015282,83150-76-9,GDF15,9518,[Celecoxib co-treated with Octreotide] results in increased expression of GDF15 mRNA,affects^cotreatment|increases^expression,1,1
Okadaic Acid,D019319,78111-17-8,GDF15,9518,Okadaic Acid results in increased expression of GDF15 mRNA,increases^expression,1,1
Organophosphates,D010755,,GDF15,9518,Organophosphates results in increased expression of GDF15 mRNA,increases^expression,1,1
origamicin,C515679,,GDF15,9518,origamicin results in increased expression of GDF15 mRNA,increases^expression,1,1
Oxygen,D010100,7782-44-7,GDF15,9518,Oxygen deficiency inhibits the reaction [darinaparsin results in decreased expression of GDF15 mRNA],decreases^expression|decreases^reaction,1,1
Oxygen,D010100,7782-44-7,GDF15,9518,Oxygen deficiency results in decreased expression of GDF15 mRNA,decreases^expression,1,1
Oxygen,D010100,7782-44-7,GDF15,9518,Oxygen deficiency results in increased expression of GDF15 mRNA,increases^expression,1,1
Oxygen,D010100,7782-44-7,GDF15,9518,Oxygen results in increased expression of GDF15 mRNA,increases^expression,1,1
Oxygen,D010100,7782-44-7,GDF15,9518,Oxygen results in increased expression of GDF15 protein,increases^expression,1,1
Paraquat,D010269,4685-14-7,GDF15,9518,Paraquat results in increased expression of GDF15 mRNA,increases^expression,3,1
Particulate Matter,D052638,,GDF15,9518,[Air Pollutants results in increased abundance of Particulate Matter analog] which results in increased expression of GDF15 mRNA,increases^abundance|increases^expression,1,1
Particulate Matter,D052638,,GDF15,9518,[Air Pollutants results in increased abundance of Particulate Matter] which results in increased expression of GDF15 mRNA,increases^abundance|increases^expression,1,1
Particulate Matter,D052638,,GDF15,9518,[[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of GDF15 mRNA,affects^cotreatment|increases^abundance|increases^expression,1,1
Particulate Matter,D052638,,GDF15,9518,[Gasoline results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of GDF15 mRNA,affects^cotreatment|increases^abundance|increases^expression,1,1
Particulate Matter,D052638,,GDF15,9518,Particulate Matter results in decreased expression of GDF15 mRNA,decreases^expression,2,1
Particulate Matter,D052638,,GDF15,9518,Particulate Matter results in increased expression of GDF15 mRNA,increases^expression,1,1
p-Chloromercuribenzoic Acid,D020245,59-85-8,GDF15,9518,"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GDF15 mRNA",affects^cotreatment|increases^expression,1,1
p-Chloromercuribenzoic Acid,D020245,59-85-8,GDF15,9518,p-Chloromercuribenzoic Acid results in increased expression of GDF15 mRNA,increases^expression,1,1
PCI 5002,C568608,,GDF15,9518,[PCI 5002 co-treated with Zinc] results in increased expression of GDF15 mRNA,affects^cotreatment|increases^expression,1,1
pentabrominated diphenyl ether 100,C517827,,GDF15,9518,pentabrominated diphenyl ether 100 results in increased expression of GDF15 protein,increases^expression,1,1
pentanal,C046012,110-62-3,GDF15,9518,pentanal results in increased expression of GDF15 mRNA,increases^expression,1,1
perfluorodecanoic acid,C036567,335-76-2,GDF15,9518,perfluorodecanoic acid results in decreased expression of GDF15 protein,decreases^expression,1,1
perfluoro-n-nonanoic acid,C101816,375-95-1,GDF15,9518,perfluoro-n-nonanoic acid results in increased expression of GDF15 mRNA,increases^expression,1,1
perfluorooctane sulfonic acid,C076994,1763-23-1,GDF15,9518,perfluorooctane sulfonic acid results in increased expression of GDF15 mRNA,increases^expression,1,1
perfluorooctanoic acid,C023036,335-67-1,GDF15,9518,perfluorooctanoic acid results in increased expression of GDF15 mRNA,increases^expression,1,1
perfluorooctanoic acid,C023036,335-67-1,GDF15,9518,perfluorooctanoic acid results in increased expression of GDF15 protein,increases^expression,1,1
perfluoroundecanoic acid,C586085,,GDF15,9518,perfluoroundecanoic acid results in decreased expression of GDF15 protein,decreases^expression,1,1
periodate-oxidized adenosine,C027579,34240-05-6,GDF15,9518,periodate-oxidized adenosine affects the expression of GDF15 mRNA,affects^expression,1,1
Phenylephrine,D010656,59-42-7,GDF15,9518,Phenylephrine affects the expression of GDF15 mRNA,affects^expression,1,1
Phenylmercuric Acetate,D010662,62-38-4,GDF15,9518,Phenylmercuric Acetate results in increased expression of GDF15 mRNA,increases^expression,1,1
Phloroglucinol,D010696,108-73-6,GDF15,9518,Phloroglucinol analog results in increased expression of GDF15 protein,increases^expression,1,1
picoxystrobin,C556557,,GDF15,9518,picoxystrobin results in increased expression of GDF15 mRNA,increases^expression,1,1
pifithrin,C121565,,GDF15,9518,pifithrin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of GDF15 mRNA],decreases^reaction|increases^expression,1,1
pinosylvin,C049032,102-61-4,GDF15,9518,pinosylvin results in increased expression of GDF15 mRNA,increases^expression,1,1
pinosylvin,C049032,102-61-4,GDF15,9518,pinosylvin results in increased expression of GDF15 protein,increases^expression,1,1
Piroxicam,D010894,36322-90-4,GDF15,9518,Cisplatin inhibits the reaction [Piroxicam results in decreased expression of GDF15 mRNA],decreases^expression|decreases^reaction,1,1
Piroxicam,D010894,36322-90-4,GDF15,9518,Piroxicam results in decreased expression of GDF15 mRNA,decreases^expression,1,1
Plant Oils,D010938,,GDF15,9518,Plant Oils results in increased expression of GDF15 mRNA,increases^expression,1,1
platycodin D,C108953,58479-68-8,GDF15,9518,platycodin D results in increased expression of GDF15 protein,increases^expression,1,1
Polycyclic Aromatic Hydrocarbons,D011084,,GDF15,9518,[[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of GDF15 mRNA,affects^cotreatment|increases^abundance|increases^expression,1,1
Polycyclic Aromatic Hydrocarbons,D011084,,GDF15,9518,[Gasoline results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of GDF15 mRNA,affects^cotreatment|increases^abundance|increases^expression,1,1
polyhexamethyleneguanidine,C060540,31961-54-3,GDF15,9518,polyhexamethyleneguanidine results in increased expression of GDF15 mRNA,increases^expression,1,1
polyhexamethyleneguanidine,C060540,31961-54-3,GDF15,9518,polyhexamethyleneguanidine results in increased expression of GDF15 protein,increases^expression,1,1
potassium chromate(VI),C027373,7789-00-6,AMH,268,[potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of AMH mRNA,affects^cotreatment|increases^expression,1,1
potassium chromate(VI),C027373,7789-00-6,AMH,268,potassium chromate(VI) results in increased expression of AMH mRNA,increases^expression,1,1
Potassium Dichromate,D011192,7778-50-9,GDF15,9518,Potassium Dichromate results in increased expression of GDF15 mRNA,increases^expression,1,1
Proadifen,D011335,302-33-0,GDF15,9518,Proadifen results in increased expression of GDF15,increases^expression,1,1
Progesterone,D011374,57-83-0,GDF15,9518,[Estradiol co-treated with Progesterone] results in decreased expression of GDF15 mRNA,affects^cotreatment|decreases^expression,1,1
Progesterone,D011374,57-83-0,GDF15,9518,Progesterone results in increased expression of GDF15 mRNA,increases^expression,1,1
propionaldehyde,C005556,123-38-6,GDF15,9518,propionaldehyde results in increased expression of GDF15 mRNA,increases^expression,1,1
prothioconazole,C550005,,AMH,268,prothioconazole results in decreased expression of AMH mRNA,decreases^expression,1,1
pterostilbene,C107773,,GDF15,9518,pterostilbene results in increased expression of GDF15 mRNA,increases^expression,1,1
pyrachlostrobin,C513428,,GDF15,9518,pyrachlostrobin results in increased expression of GDF15 mRNA,increases^expression,1,1
pyrazolanthrone,C432165,,GDF15,9518,pyrazolanthrone promotes the reaction [Silybin results in increased expression of GDF15 protein],increases^expression|increases^reaction,1,1
pyrimidifen,C476509,,AMH,268,pyrimidifen results in increased expression of AMH mRNA,increases^expression,1,1
pyrimidifen,C476509,,GDF15,9518,pyrimidifen results in increased expression of GDF15 mRNA,increases^expression,1,1
pyrithione zinc,C010423,,GDF15,9518,pyrithione zinc results in increased expression of GDF15 mRNA,increases^expression,1,1
Quercetin,D011794,117-39-5,GDF15,9518,Quercetin results in decreased expression of GDF15 mRNA,decreases^expression,1,1
Quercetin,D011794,117-39-5,GDF15,9518,Quercetin results in increased expression of GDF15 mRNA,increases^expression,1,1
Resveratrol,D000077185,,GDF15,9518,Dactinomycin inhibits the reaction [Resveratrol results in increased expression of GDF15 mRNA],decreases^reaction|increases^expression,1,1
Resveratrol,D000077185,,GDF15,9518,[indole-3-carbinol co-treated with Resveratrol] results in increased expression of GDF15,affects^cotreatment|increases^expression,1,1
Resveratrol,D000077185,,GDF15,9518,Resveratrol metabolite results in increased expression of GDF15 protein,increases^expression,1,1
Resveratrol,D000077185,,GDF15,9518,Resveratrol promotes the reaction [[TP53 protein binds to GDF15 promoter] which results in increased expression of GDF15 mRNA],affects^binding|increases^expression|increases^reaction,1,1
Resveratrol,D000077185,,GDF15,9518,Resveratrol results in increased expression of GDF15 mRNA,increases^expression,2,1
Resveratrol,D000077185,,GDF15,9518,Resveratrol results in increased expression of GDF15 protein,increases^expression,1,1
Resveratrol,D000077185,,GDF15,9518,[Resveratrol results in increased expression of TP53] promotes the reaction [[TP53 protein binds to GDF15 promoter] which results in increased expression of GDF15],affects^binding|increases^expression|increases^reaction,1,1
Resveratrol,D000077185,,GDF15,9518,[Resveratrol results in increased expression of TP53 protein] which results in increased expression of GDF15 protein,increases^expression,1,1
Ro 31-8220,C064758,125314-64-9,GDF15,9518,Ro 31-8220 inhibits the reaction [gingerol results in increased expression of GDF15 protein],decreases^reaction|increases^expression,1,1
Rosiglitazone,D000077154,,GDF15,9518,Rosiglitazone results in increased expression of GDF15 mRNA,increases^expression,3,1
Rotenone,D012402,83-79-4,AMH,268,Rotenone results in decreased expression of AMH mRNA,decreases^expression,1,1
Rotenone,D012402,83-79-4,AMH,268,Rotenone results in increased expression of AMH mRNA,increases^expression,1,1
Rotenone,D012402,83-79-4,GDF15,9518,Rotenone results in increased expression of GDF15 mRNA,increases^expression,2,1
rottlerin,C085746,82-08-6,GDF15,9518,2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [rottlerin results in increased expression of GDF15 protein],decreases^reaction|increases^expression,1,1
rottlerin,C085746,82-08-6,GDF15,9518,GDF15 affects the susceptibility to rottlerin,affects^response to substance,1,1
rottlerin,C085746,82-08-6,GDF15,9518,rottlerin results in increased expression of GDF15 mRNA,increases^expression,1,1
rottlerin,C085746,82-08-6,GDF15,9518,rottlerin results in increased expression of GDF15 protein,increases^expression,1,1
rottlerin,C085746,82-08-6,GDF15,9518,SB 203580 inhibits the reaction [rottlerin results in increased expression of GDF15 protein],decreases^reaction|increases^expression,1,1
"S-(1,2-dichlorovinyl)cysteine",C039961,627-72-5,GDF15,9518,"[S-(1,2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of GDF15 mRNA",affects^cotreatment|decreases^expression,1,1
"S-(1,2-dichlorovinyl)cysteine",C039961,627-72-5,GDF15,9518,"S-(1,2-dichlorovinyl)cysteine results in increased expression of GDF15 mRNA",increases^expression,1,1
SB 203580,C093642,,GDF15,9518,[SB 203580 co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] inhibits the reaction [jasplakinolide results in increased expression of GDF15 protein],affects^cotreatment|decreases^reaction|increases^expression,1,1
SB 203580,C093642,,GDF15,9518,[SB 203580 co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] inhibits the reaction [latrunculin B results in increased expression of GDF15 protein],affects^cotreatment|decreases^reaction|increases^expression,1,1
SB 203580,C093642,,GDF15,9518,[SB 203580 co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GDF15 protein],affects^cotreatment|decreases^reaction|increases^expression,1,1
SB 203580,C093642,,GDF15,9518,SB 203580 inhibits the reaction [rottlerin results in increased expression of GDF15 protein],decreases^reaction|increases^expression,1,1
SB 203580,C093642,,GDF15,9518,SB 203580 inhibits the reaction [Silybin results in increased expression of GDF15 protein],decreases^reaction|increases^expression,1,1
SB 216763,C417521,,GDF15,9518,SB 216763 inhibits the reaction [Celecoxib results in increased expression of GDF15],decreases^reaction|increases^expression,1,1
SC 560,C115461,,GDF15,9518,SC 560 results in increased expression of GDF15 mRNA,increases^expression,1,1
SC 560,C115461,,GDF15,9518,SC 560 results in increased expression of GDF15 protein,increases^expression,2,1
securinine,C000785,5610-40-2,GDF15,9518,securinine results in increased expression of GDF15 mRNA,increases^expression,1,1
shogaol,C040115,555-66-8,GDF15,9518,shogaol results in increased expression of GDF15 mRNA,increases^expression,1,1
Silicon Dioxide,D012822,7631-86-9,GDF15,9518,Silicon Dioxide analog results in increased expression of GDF15 mRNA,increases^expression,1,1
Silver Compounds,D018030,,GDF15,9518,Silver Compounds results in increased expression of GDF15 mRNA,increases^expression,1,1
Silybin,D000077385,22888-70-6,GDF15,9518,EGR1 mutant form inhibits the reaction [Silybin results in increased expression of GDF15 protein],decreases^reaction|increases^expression,1,1
Silybin,D000077385,22888-70-6,GDF15,9518,GDF15 mutant form inhibits the reaction [Silybin results in increased cleavage of PARP1 protein],decreases^reaction|increases^cleavage,1,1
Silybin,D000077385,22888-70-6,GDF15,9518,pyrazolanthrone promotes the reaction [Silybin results in increased expression of GDF15 protein],increases^expression|increases^reaction,1,1
Silybin,D000077385,22888-70-6,GDF15,9518,SB 203580 inhibits the reaction [Silybin results in increased expression of GDF15 protein],decreases^reaction|increases^expression,1,1
Silybin,D000077385,22888-70-6,GDF15,9518,Silybin results in increased expression of GDF15 mRNA,increases^expression,1,1
Silybin,D000077385,22888-70-6,GDF15,9518,Silybin results in increased expression of GDF15 protein,increases^expression,1,1
Smoke,D012906,,AMH,268,Smoke results in decreased expression of AMH mRNA,decreases^expression,1,1
Smoke,D012906,,GDF15,9518,Smoke results in decreased expression of GDF15 mRNA,decreases^expression,1,1
S-Nitrosoglutathione,D026422,57564-91-7,GDF15,9518,S-Nitrosoglutathione results in increased expression of GDF15 mRNA,increases^expression,1,1
sodium arsenite,C017947,13768-07-5,AMH,268,sodium arsenite results in increased expression of AMH mRNA,increases^expression,1,1
sodium arsenite,C017947,13768-07-5,GDF15,9518,[sodium arsenite affects the acetylation of H3-4 protein] which affects the methylation of GDF15 promoter,affects^acetylation|affects^methylation,1,1
sodium arsenite,C017947,13768-07-5,GDF15,9518,[sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of GDF15 mRNA,affects^cotreatment|decreases^expression,1,1
sodium arsenite,C017947,13768-07-5,GDF15,9518,sodium arsenite results in decreased expression of GDF15 mRNA,decreases^expression,2,1
sodium arsenite,C017947,13768-07-5,GDF15,9518,sodium arsenite results in increased expression of GDF15 mRNA,increases^expression,5,1
sodium arsenite,C017947,13768-07-5,GDF15,9518,sodium arsenite results in increased expression of GDF15 protein,increases^expression,1,1
Sodium Selenite,D018038,10102-18-8,GDF15,9518,Sodium Selenite results in increased expression of GDF15 mRNA,increases^expression,1,1
sulforaphane,C016766,,AMH,268,sulforaphane results in increased expression of AMH mRNA,increases^expression,1,1
Sulindac,D013467,38194-50-2,GDF15,9518,Sulindac results in increased expression of GDF15 mRNA,increases^expression,1,1
Sulindac,D013467,38194-50-2,GDF15,9518,Sulindac results in increased expression of GDF15 protein,increases^expression,1,1
sulindac sulfide,C025462,32004-67-4,GDF15,9518,EGR1 protein promotes the reaction [sulindac sulfide results in increased expression of GDF15 mRNA],increases^expression|increases^reaction,1,1
sulindac sulfide,C025462,32004-67-4,GDF15,9518,sulindac sulfide results in increased expression of GDF15 mRNA,increases^expression,1,1
sulindac sulfide,C025462,32004-67-4,GDF15,9518,sulindac sulfide results in increased expression of GDF15 protein,increases^expression,7,1
Sunitinib,D000077210,,GDF15,9518,Sunitinib results in increased expression of GDF15 mRNA,increases^expression,1,1
T-2 Toxin,D013605,21259-20-1,GDF15,9518,T-2 Toxin results in increased expression of GDF15 mRNA,increases^expression,1,1
Tamoxifen,D013629,10540-29-1,GDF15,9518,GDF15 protein results in decreased susceptibility to Tamoxifen,decreases^response to substance,1,1
taxifolin,C003377,480-18-2,GDF15,9518,taxifolin results in increased expression of GDF15 mRNA,increases^expression,1,1
Temozolomide,D000077204,85622-93-1,GDF15,9518,Temozolomide results in increased expression of GDF15 mRNA,increases^expression,1,1
tert-Butylhydroperoxide,D020122,,GDF15,9518,tert-Butylhydroperoxide results in increased expression of GDF15 mRNA,increases^expression,1,1
tetrabromobisphenol A,C020806,79-94-7,GDF15,9518,[PPARG protein results in increased susceptibility to tetrabromobisphenol A] which results in increased expression of GDF15 mRNA,increases^expression|increases^response to substance,1,1
tetrabromobisphenol A,C020806,79-94-7,GDF15,9518,tetrabromobisphenol A results in increased expression of GDF15 protein,increases^expression,1,1
Tetrachlorodibenzodioxin,D013749,1746-01-6,GDF15,9518,[Endosulfan co-treated with Tetrachlorodibenzodioxin] results in increased expression of GDF15 mRNA,affects^cotreatment|increases^expression,1,1
Tetrachlorodibenzodioxin,D013749,1746-01-6,GDF15,9518,[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of GDF15 mRNA,affects^cotreatment|increases^expression,1,1
Tetrachlorodibenzodioxin,D013749,1746-01-6,GDF15,9518,pifithrin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of GDF15 mRNA],decreases^reaction|increases^expression,1,1
Tetrachlorodibenzodioxin,D013749,1746-01-6,GDF15,9518,Tetrachlorodibenzodioxin affects the expression of GDF15 mRNA,affects^expression,1,1
Tetrachlorodibenzodioxin,D013749,1746-01-6,GDF15,9518,Tetrachlorodibenzodioxin results in decreased expression of GDF15 mRNA,decreases^expression,1,1
Tetrachlorodibenzodioxin,D013749,1746-01-6,GDF15,9518,Tetrachlorodibenzodioxin results in increased expression of GDF15 mRNA,increases^expression,5,1
Tetradecanoylphorbol Acetate,D013755,16561-29-8,GDF15,9518,[Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GDF15 protein,affects^cotreatment|decreases^expression,1,1
Tetradecanoylphorbol Acetate,D013755,16561-29-8,GDF15,9518,[SB 203580 co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GDF15 protein],affects^cotreatment|decreases^reaction|increases^expression,1,1
Tetradecanoylphorbol Acetate,D013755,16561-29-8,GDF15,9518,Tetradecanoylphorbol Acetate results in increased expression of GDF15 protein,increases^expression,1,1
Thapsigargin,D019284,67526-95-8,GDF15,9518,Thapsigargin results in increased expression of GDF15 mRNA,increases^expression,1,1
Theophylline,D013806,58-55-9,GDF15,9518,[Hydrogen Peroxide co-treated with Theophylline] results in decreased expression of GDF15 protein,affects^cotreatment|decreases^expression,1,1
thifluzamide,C494892,,GDF15,9518,thifluzamide results in increased expression of GDF15 mRNA,increases^expression,1,1
Thiostrepton,D013883,1393-48-2,GDF15,9518,Thiostrepton results in increased expression of GDF15 mRNA,increases^expression,1,1
Thiram,D013893,137-26-8,AMH,268,Thiram results in increased expression of AMH mRNA,increases^expression,1,1
Thiram,D013893,137-26-8,GDF15,9518,Thiram results in increased expression of GDF15 mRNA,increases^expression,1,1
titanium dioxide,C009495,13463-67-7,GDF15,9518,[Vitallium analog binds to titanium dioxide] which results in increased expression of GDF15 mRNA,affects^binding|increases^expression,1,1
Tobacco Smoke Pollution,D014028,,AMH,268,Tobacco Smoke Pollution affects the expression of AMH mRNA,affects^expression,1,1
Tobacco Smoke Pollution,D014028,,GDF15,9518,Tobacco Smoke Pollution affects the expression of GDF15 protein,affects^expression,1,1
Tobacco Smoke Pollution,D014028,,GDF15,9518,Tobacco Smoke Pollution results in increased expression of GDF15 mRNA,increases^expression,2,1
Tretinoin,D014212,302-79-4,GDF15,9518,Tretinoin metabolite results in increased expression of GDF15 mRNA,increases^expression,1,1
Tretinoin,D014212,302-79-4,GDF15,9518,Tretinoin results in decreased expression of GDF15 mRNA,decreases^expression,1,1
Tretinoin,D014212,302-79-4,GDF15,9518,Tretinoin results in increased expression of GDF15 mRNA,increases^expression,2,1
trichostatin A,C012589,58880-19-6,GDF15,9518,Cycloheximide inhibits the reaction [trichostatin A affects the expression of GDF15 mRNA],affects^expression|decreases^reaction,1,1
trichostatin A,C012589,58880-19-6,GDF15,9518,Cycloheximide inhibits the reaction [trichostatin A affects the expression of GDF15 protein],affects^expression|decreases^reaction,1,1
trichostatin A,C012589,58880-19-6,GDF15,9518,Decitabine promotes the reaction [[trichostatin A affects the methylation of GDF15 promoter] which affects the expression of GDF15 mRNA],affects^expression|affects^methylation|increases^reaction,1,1
trichostatin A,C012589,58880-19-6,GDF15,9518,Decitabine promotes the reaction [[trichostatin A affects the methylation of GDF15 promoter] which affects the expression of GDF15 protein],affects^expression|affects^methylation|increases^reaction,1,1
trichostatin A,C012589,58880-19-6,GDF15,9518,EGR1 protein affects the reaction [trichostatin A affects the expression of GDF15 mRNA],affects^expression|affects^reaction,1,1
trichostatin A,C012589,58880-19-6,GDF15,9518,SP1 protein affects the reaction [trichostatin A affects the expression of GDF15 mRNA],affects^expression|affects^reaction,1,1
trichostatin A,C012589,58880-19-6,GDF15,9518,trichostatin A results in increased expression of GDF15 mRNA,increases^expression,1,1
trichostatin A,C012589,58880-19-6,GDF15,9518,[trichostatin A results in increased expression of GDF15 protein] which results in increased cleavage of PARP1 protein,increases^cleavage|increases^expression,1,1
trichostatin A,C012589,58880-19-6,GDF15,9518,[trichostatin A results in increased stability of GDF15 mRNA] which results in increased expression of GDF15 protein,increases^expression|increases^stability,1,1
"tris(1,3-dichloro-2-propyl)phosphate",C016805,13674-87-8,GDF15,9518,"tris(1,3-dichloro-2-propyl)phosphate results in increased expression of GDF15 mRNA",increases^expression,1,1
Troglitazone,D000077288,97322-87-7,GDF15,9518,2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Troglitazone results in increased expression of GDF15 protein],decreases^reaction|increases^expression,1,1
Troglitazone,D000077288,97322-87-7,GDF15,9518,Cycloheximide inhibits the reaction [Troglitazone results in increased expression of GDF15 mRNA],decreases^reaction|increases^expression,1,1
Troglitazone,D000077288,97322-87-7,GDF15,9518,[EGR1 protein binds to GDF15 promoter] affects the reaction [Troglitazone results in increased expression of GDF15],affects^binding|affects^reaction|increases^expression,1,1
Troglitazone,D000077288,97322-87-7,GDF15,9518,Troglitazone results in increased expression of GDF15 mRNA,increases^expression,3,1
Troglitazone,D000077288,97322-87-7,GDF15,9518,Troglitazone results in increased expression of GDF15 protein,increases^expression,3,1
tungsten carbide,C002802,11130-73-7,GDF15,9518,[tungsten carbide binds to Cobalt] which affects the expression of GDF15 mRNA,affects^binding|affects^expression,1,1
Tungsten Compounds,D017973,,GDF15,9518,Tungsten Compounds results in increased expression of GDF15 mRNA,increases^expression,1,1
Tunicamycin,D014415,11089-65-9,GDF15,9518,Tunicamycin results in increased expression of GDF15 mRNA,increases^expression,1,1
Urethane,D014520,51-79-6,GDF15,9518,Urethane results in increased expression of GDF15 mRNA,increases^expression,1,1
Valproic Acid,D014635,99-66-1,AMH,268,Valproic Acid results in decreased expression of AMH mRNA,decreases^expression,1,1
Valproic Acid,D014635,99-66-1,AMH,268,Valproic Acid results in increased methylation of AMH gene,increases^methylation,1,1
Valproic Acid,D014635,99-66-1,GDF15,9518,Valproic Acid affects the expression of GDF15 mRNA,affects^expression,1,1
Valproic Acid,D014635,99-66-1,GDF15,9518,Valproic Acid results in increased expression of GDF15 mRNA,increases^expression,4,1
vanadium pentoxide,C066075,1314-62-1,GDF15,9518,vanadium pentoxide results in increased expression of GDF15 mRNA,increases^expression,1,1
Vincristine,D014750,,GDF15,9518,Vincristine results in increased expression of GDF15 mRNA,increases^expression,1,1
Vitallium,D014800,12629-02-6,GDF15,9518,[Vitallium analog binds to titanium dioxide] which results in increased expression of GDF15 mRNA,affects^binding|increases^expression,1,1
Vitallium,D014800,12629-02-6,GDF15,9518,Vitallium analog results in increased expression of GDF15 mRNA,increases^expression,1,1
Vitamin K 3,D024483,58-27-5,GDF15,9518,Vitamin K 3 affects the expression of GDF15 mRNA,affects^expression,1,1
Vitamin K 3,D024483,58-27-5,GDF15,9518,Vitamin K 3 results in increased expression of GDF15 mRNA,increases^expression,1,1
Water Pollutants,D014873,,GDF15,9518,[Water Pollutants results in increased abundance of naphthenic acid] which results in increased expression of GDF15 mRNA,increases^abundance|increases^expression,1,1
Water Pollutants,D014873,,GDF15,9518,[Water Pollutants results in increased abundance of naphthenic acid] which results in increased secretion of GDF15 protein,increases^abundance|increases^secretion,1,1
Wortmannin,D000077191,19545-26-7,GDF15,9518,Wortmannin results in increased expression of GDF15 protein,increases^expression,1,1
Zinc,D015032,7440-66-6,GDF15,9518,[PCI 5002 co-treated with Zinc] results in increased expression of GDF15 mRNA,affects^cotreatment|increases^expression,1,1
zinc chromate,C023616,13530-65-9,GDF15,9518,[zinc chromate results in increased abundance of chromium hexavalent ion] which results in increased expression of GDF15 mRNA,increases^abundance|increases^expression,1,1
Zoledronic Acid,D000077211,,GDF15,9518,Zoledronic Acid results in decreased expression of GDF15 mRNA,decreases^expression,2,1
